Research Services

Cytogenomic Microarray Analysis for Research

The constitutional chromosomal microarray analysis and the neoplasia chromosomal microarray analysis can both be ordered as part of research studies. Call the Laboratory Director (206-685-1170) for more details.

Turnaround Time: 28 days from receipt of adequate sample

Test Requisition: Research Service Request Form

Constitutional CMA Specimen Types:

  • Peripheral Blood: 3-5 ml in EDTA (lavender top vacutainer). Keep at room temperature.
  • Cord Blood: 1-2 ml in EDTA (lavender top vacutainer). Keep at room temperature.
  • Products of Conception and Fetal Tissue: 30-50mg fresh tissue in sterile transport media or two T-25 flasks 80-100% confluent. If identifiable tissue in products of conception, send chorionic villi. If material is small and unidentifiable, send entire sample.  For stillbirths, send fascia lata, lung, or kidney if possible. Keep refrigerated.
  • Amniotic Fluid: 15-20ml of amniotic fluid OR two T-25 flasks that are 80-100% confluent. Keep at room temperature.
  • Chorionic Villi: Two T-25 flasks that are 80-100% confluent. Keep at room temperature.
  • DNA: 3-10 micrograms of DNA (minimum 1 microgram) at a concentration of 100 nanograms per microliter (or higher) suspended in TE-buffer. Keep at room temperature.
  • Saliva: 0.5mL in Oragene•ONE(ON-500) Collection Kit. Keep at room temperature.

Neoplasia Specimen Types:

  • Leukemic Blood: 1-3 ml in EDTA (lavender top vacutainer). Keep at room temperature.
  • Bone Marrow: 1-3 ml in EDTA (lavender top vacutainer). Keep at room temperature.
  • Fresh Frozen Tumor Tissue: 50-150mg (0.15-2.0 cm3) fresh tissue snap-frozen. Store at -20°C. Ship on minimum of 10 lb of dry ice in insulated container by overnight courier.
  • FFPE Tumor Slides: 10 unstained 5μm FFPE slides containing adequate amounts of tumor with areas of tumor marked. Include a copy of corresponding surgical pathology report. Mail slides in a protected mailing container at 20-25°C and protect from excessive heat.
  • FFPE Tumor Block: Tissue block containing adequate amounts of tumor with areas of tumor marked. Include a copy of corresponding surgical pathology report. Mail at 20-25°C and protect from excessive heat.
  • Solid Tumor Cultures: Two T-25 flasks that are 80-100% confluent. Keep at room temperature.
  • Bone Core: Contact the lab (206-598-4488).
  • Lymph Node: Contact the lab (206-598-4488).
  • DNA: 3-10 micrograms of DNA suspended in TE-buffer.

Deliver to laboratory as soon as possible. Specimens are accepted 7 days a week.

Ship sample overnight to:

Cytogenetics and Genomics Laboratory
University of Washington Medical Center
Room NW-125, Box 356100
1959 NE Pacific St
Seattle, WA 98195-6100

Phone 206-598-4488